The Icebox

WRKY Transcription Factors

WRKY transcription factors are DNA-binding proteins regulating the expression of many plant and algae genes, especially responses to stress, development, and germination. The protein structure of WRKY TFs includes a DNA-binding domain (called the WRKY domain), and recognises a highly conserved DNA sequence. The WRKY domain also has a zinc-finger structure, but this may not be able to bind DNA [unsure].

WRKY transcription factors may be involved in plant pathogen-associated molecular pattern immune responses. For example, on Arabidopsis thaliana exposure to FLG22, a MAP kinase cascade occurs, activating a WRKY transcription factor. This will induce gene expression. The exact pathway after this point is not well understood, however it may activate PMR4 and induce callose synthesis. This would be a response to biotic stresses.

Refs:
https://en.wikipedia.org/wiki/WRKY_transcription_factor https://pubmed.ncbi.nlm.nih.gov/20304701/ https://bmcplantbiol.biomedcentral.com/articles/10.1186/1471-2229-7-2